What era are you referring to?
One of the more famous yogis [sorry cannot recall his name] has an institute there currently. Santa Fe Community
College currently has a campus in Keystone
Heights.
Since
Melrose straddles four counties [Alachua,
Bradford,
Clay, and
Putnam], you may need to check the county histories of each. Looking at "The River Flows North: A History of
Putnam County" by Brian
Michaels, I am not findin any kind of college or university there.